How does ZILBRYSQ (zilucoplan) work?
The US label describes zilucoplan as a complement C5 inhibitor for adults with AChR-antibody-positive generalized myasthenia gravis. Its boxed warning concerns serious meningococcal infections. A clinician must assess suitability; Uwell coordinates inquiries and does not prescribe medicines.
What is it used for?
ZILBRYSQ is indicated for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive.ZILBRYSQ is indicated for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive.
Read the primary sourceThis source does not establish current stock, import permission or personal eligibility in China. The treating clinician and provider must confirm these separately.
Product details
- Active ingredient
- zilucoplanzilucoplan
- Form and strength
- INJECTION, SOLUTION · 40 mg / 1 mLINJECTION, SOLUTION · 40 mg / 1 mL
- Manufacturer / applicant
- UCB, INC.UCB, INC.
Injection: 16.6 mg/0.416 mL, 23 mg/0.574 mL, or 32.4 mg/0.81 mL of zilucoplan as a clear to slightly opalescent, colorless solution in single-dose prefilled syringes.Injection: 16.6 mg/0.416 mL, 23 mg/0.574 mL, or 32.4 mg/0.81 mL of zilucoplan as a clear to slightly opalescent, colorless solution in single-dose prefilled syringes.
Safety and clinical review
ZILBRYSQ, a complement inhibitor, increases the risk of serious infections caused by Neisseria meningitidis . Life-threatening and fatal meningococcal infections have occurred in patients treated with complement inhibitors. These infections may become rapidly life-threatening or fatal if not recognized and treated early. …ZILBRYSQ, a complement inhibitor, increases the risk of serious infections caused by Neisseria meningitidis . Life-threatening and fatal meningococcal infections have occurred in patients treated with complement inhibitors. These infections may become rapidly life-threatening or fatal if not recognized and treated early. …
- Serious Meningococcal InfectionsSerious Meningococcal Infections
- ZILBRYSQ REMSZILBRYSQ REMS
- Other InfectionsOther Infections
- Pancreatitis and Other Pancreatic ConditionsPancreatitis and Other Pancreatic Conditions
Ask your clinician to review the complete label, medical history, other medicines, allergies, pregnancy or breastfeeding and any required monitoring. Do not start, stop or change treatment from this page.
Read the primary sourcePrepare your enquiry
Include the brand or generic name, strength, dosage form, requested quantity and country where care is needed. You can attach a prescription when you continue.
Questions patients ask
What is ZILBRYSQ used for?
ZILBRYSQ is indicated for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive.ZILBRYSQ is indicated for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive.
This source does not establish current stock, import permission or personal eligibility in China. The treating clinician and provider must confirm these separately.
Which formulation of ZILBRYSQ should I ask about?
INJECTION, SOLUTION · 40 mg / 1 mLINJECTION, SOLUTION · 40 mg / 1 mL
Read the primary sourceWhat determines the price of ZILBRYSQ?
A current quote depends on the exact presentation, quantity, provider and access arrangements. A catalogue entry is not a stock or delivery promise. Medical charges are paid to the provider, separately from coordination fees.
What should I check before using ZILBRYSQ?
Ask your clinician to review the complete label, medical history, other medicines, allergies, pregnancy or breastfeeding and any required monitoring. Do not start, stop or change treatment from this page.
Sources and review scope
FDA prescribing informationThis source does not establish current stock, import permission or personal eligibility in China. The treating clinician and provider must confirm these separately.