GLEOSTINE lomustine
洛莫司汀
Drug Class
Alkylating agent烷化剂
Mechanism
Alkylates DNA and RNA, cross-linking nucleic acid strands and inhibiting macromolecular synthesis in cancer cells.使 DNA 和 RNA 烷基化，导致核酸链交联并抑制癌细胞中的大分子合成。
Approved Indication
Treatment of patients with brain tumors (primary and metastatic) and Hodgkin's lymphoma (as second-line therapy), in addition to other modalities or in combination regimens.作为联合治疗或单药方案，用于治疗脑肿瘤（原发性和转移性）以及霍奇金淋巴瘤（作为二线治疗）。
What This Means For Patients
GLEOSTINE is not distributed through mainland China's retail pharmacy network. Uwell Cloud can help arrange a purchase channel for this medicine, sourced and dispatched from Hong Kong; clinical administration support in China can be coordinated on request. Availability and eligibility for any specific patient are determined by clinical review.GLEOSTINE（洛莫司汀）目前未通过中国大陆零售药房渠道销售。优健云可协助安排购买渠道，药品由香港采购发货；如有需要，可协调来华后的临床用药支持。具体供应及患者适用性以医疗预检评估为准。
Regulatory Approvals
Not yet documented.
Pivotal Clinical Evidence
No peer-reviewed pivotal trial on file yet.